Monday, 14 July 2014

Microangiopathy small branching arterial bed

Of purposefully examined 600 patients with diabetes diabetic enteropathy was diagnosed in 16 patients - 2.7%. 10 patients had diabetic diarrhea, steatorrhea 6 patients, none of the patients had a combination of them. Steatorrhea documented fat in the daily amount of more than 8

grams of feces on admission intake of 60-80 grams of fat (fat in the feces was determined by van de camera). In all patients with diabetic enteropathy duration of diabetes over 5 years (11 of 16 patients - more than 10 years)

. In 9 of 10 patients with diarrhea and in 4 of 6 patients with steatorrhea carbohydrate metabolism poorly monitored throughout the period of diabetes . In 8 out of 10 patients with diabetic retinopathy diarrhea was observed, and 4 patients - neuropathy. In 6 of the 10 diabetic patients with diarrhea

we conducted a test with oral d-xylose load and two of these patients reported a decrease in the magnitude of daily excretion of pentoses.

All 6 patients with diabetes in combination with steatorrhea diabetes duration greater than 5 years, everyone has been found retinopathy, evidence of neuropathy in these patients was not. In 3 of 5 patients with diabetic steatorrhea after load d-xylose daily urinary excretion of pentose turned Discount.   

Microangiopathy small branching arterial bed of the small intestine, autonomic neuropathy, nerve plexus of the intestine, in some cases, atrophy of the mucosa of the small intestine, changes in the structure of the intestinal microflora - these are the main pathogenetic mechanisms of diabetic enteropathy.

As the enzymes of the pancreas , the exocrine part of it produced and secreted into the lumen of the intestine, play an important role in physiological processes intestinal absorption, it is useful to analyze the functional state of exocrine pancreas in patients with diabetes.

In portions of duodenal contents, taken on an empty stomach, decreased lipase activity in 13 patients, amylase and trypsin at 7 - 3 out of 37 surveyed, curves fermentovydeleniya violations

 were found in half of the number of people with diabetes. In diabetic patients, significant fluctuations in the activity of pancreatic enzymes duodenal contents with a tendency to oppression in severe  

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